Best supportive care: Definition, Uses, and Clinical Overview

Best supportive care is a structured approach to preventing and relieving symptoms and stress related to cancer and its treatment. It focuses on comfort, function, and quality of life while aligning care with a person’s goals and values. It is used across the cancer journey, from diagnosis through treatment, survivorship, and end-of-life care. It is delivered by oncology teams and often includes palliative care specialists, nurses, pharmacists, social workers, and rehabilitation clinicians.

Restaging scan: Definition, Uses, and Clinical Overview

A Restaging scan is imaging done to reassess the extent of cancer after a known diagnosis. It is commonly used during or after treatment to see whether cancer has responded, stayed stable, or progressed. It helps clinicians compare current findings with earlier scans and clinical information. It is used across medical oncology, radiation oncology, surgical oncology, and hematology-oncology.

Baseline imaging: Definition, Uses, and Clinical Overview

Baseline imaging is the first set of medical scans done around the time a cancer is diagnosed or before treatment starts. It creates a “starting point” picture of where disease is and how large it appears. It is commonly used in oncology clinics, hospitals, and radiation therapy planning services. It helps clinicians compare future scans to see whether cancer is responding or changing.

Charlson comorbidity index: Definition, Uses, and Clinical Overview

The Charlson comorbidity index is a scoring system that summarizes a person’s other medical conditions into a single number. It helps clinicians and researchers describe overall health burden (“comorbidity”) alongside a cancer diagnosis. It is commonly used in oncology clinics, hospitals, and cancer research to estimate health risks and support planning. It does not diagnose cancer or replace cancer staging, but it can add important context.

Comorbidity index: Definition, Uses, and Clinical Overview

A Comorbidity index is a structured way to summarize a person’s other health conditions alongside cancer. It turns multiple diagnoses (such as diabetes or heart disease) into a single score or category. Oncology teams use it to support risk assessment, treatment planning, and clear communication. Researchers also use it to compare outcomes across patient groups more fairly.

Frailty assessment: Definition, Uses, and Clinical Overview

Frailty assessment is a structured way to measure a person’s overall physiologic reserve and vulnerability to stress. It looks beyond age and diagnoses to understand function, nutrition, cognition, mood, and social supports. In oncology, it is commonly used before cancer treatment to help tailor care to the individual. It may be done in clinics, hospitals, and pre-operative or chemotherapy planning settings.

Karnofsky performance status: Definition, Uses, and Clinical Overview

Karnofsky performance status is a standardized scale that describes how well a person can carry out everyday activities. It is commonly used in oncology to summarize functional ability on a 0–100 scale. Clinicians use it to support treatment planning, symptom management, and communication across care teams.

ECOG performance status: Definition, Uses, and Clinical Overview

ECOG performance status is a clinical scale that describes how well a person can carry out everyday activities. It helps oncology teams summarize overall functioning using a small set of standardized categories. It is commonly used in cancer clinics, hospital oncology services, and clinical trials. It supports shared understanding when planning treatment and supportive care.

Performance status: Definition, Uses, and Clinical Overview

Performance status is a clinical way to describe how well a person can do everyday activities while living with cancer. It summarizes function—such as walking, working, and self-care—into a simple score. It is commonly used in oncology clinics, hospitals, and clinical trials. It helps teams communicate clearly about a patient’s overall fitness for different treatment options.

EMT: Definition, Uses, and Clinical Overview

EMT stands for epithelial–mesenchymal transition. It is a biological process where cells change from a tightly connected “epithelial” state to a more mobile “mesenchymal” state. In cancer, EMT is commonly discussed to help explain invasion, spread (metastasis), and treatment resistance. It is used most often in oncology research and in interpreting tumor biology rather than as a standalone clinical procedure.